Immunocompetent Mouse Model of Pancreatic Cancer
نویسندگان
چکیده
Author manuscripts have been peer reviewed and accepted for publication but have not yet been edited. Copyright © 2010 American Association for Cancer Research Development of an orthotopic model of invasive pancreatic cancer in an immunocompetent murine host William W. Tseng , Daniel Winer , Justin A. Kenkel, Okmi Choi, Alan H. Shain, Jonathan R. Pollack, Randy French, Andrew M. Lowy , Edgar G. Engleman 1
منابع مشابه
Development of an orthotopic model of invasive pancreatic cancer in an immunocompetent murine host.
PURPOSE The most common preclinical models of pancreatic adenocarcinoma utilize human cells or tissues that are xenografted into immunodeficient hosts. Several immunocompetent, genetically engineered mouse models of pancreatic cancer exist; however, tumor latency and disease progression in these models are highly variable. We sought to develop an immunocompetent, orthotopic mouse model of pancr...
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